I'm in Central Indiana (about 20 minutes north of Indianapolis), and my house is just under 150 miles from there. Time-wise, it depends on traffic and construction. The longest it's taken me from my house is about 2 1/2 hours when I first started driving there; the Apple Maps app took me the I-70 E way, which consisted of a ton of backroads. Now, it takes me about 2 hours, as going on the interstate for about 95% of my drive allows me to go a higher speed. Once I get out of town, I'll take I-465 S to I-74 E to I-275 E/S to I-71 to Kings Island Drive.